The lyrics, a first-person narrative, appear to relate the story of a man pleading with a woman to let him in her house; the speaker calls himself "Papa McTell" in the first stanza ("Have you got the nerve to drive Papa McTell from your door?"). Throughout the song, the woman, addressed as "mama," is alternately pleaded with (to go with the speaker "up the country") and threatened ("When I leave this time, pretty mama, I'm going away to stay"). Throughout the non-linear narrative, the "Statesboro blues" are invoked—an unexplained condition from which the speaker and his entire family seem to be suffering ("I woke up this morning / Had them Statesboro blues / I looked over in the corner: grandma and grandpa had 'em too").
That's my kindof analysis.